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USMLE USMLE : United States Medical Licensing Examination

Exam Code: USMLE

Exam Name: United States Medical Licensing Examination

Updated: Aug 16, 2026

Q & A: 400 Questions and Answers

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USMLE United States Medical Licensing Examination

USMLE stands for United States Medical Licensing Examination. This is a series of medical exams coming in a few stages that all new doctors need to pass (starting from their time in med school) to be able to practice medicine.

USMLE Step 1 is a one-day (8 hours) examination. It includes 322 multiple-choice questions divided into 7 blocks of 46 items (60 minutes are given for completion of each block).

USMLE USMLE Exam Syllabus Topics:

TopicDetails
Topic 1
  • Biology of tissue response to disease
  • Disorders of balance and spatial orientation
Topic 2
  • Adverse effects of drugs on the hematologic and lymphoreticular systems
  • Disorders associated with immunodeficiency
Topic 3
  • Infectious and inflammatory disorders of the eye
  • Adverse effects of drugs on the immune system
Topic 4
  • Adaptive behavioral responses to stress and illness
  • Biochemistry and molecular biology
Topic 5
  • Deficiency of phagocytic cells and natural killer cells
  • Adverse effects of drugs on the nervous system
Topic 6
  • Eating disorders and impulse control disorders
  • Pharmacodynamic and pharmacokinetic processes

Reference: http://www.usmle.org/step-1/#question-formats

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